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Epidural scar tissue is composed of bands of fibrous material which is attached to nerve roots, the dura, and the side walls of the epidural space. Such scar tissue may form as a consequence of spine surgery in which the epidural space is entered (discectomy, laminectomy, Brantigan cage fusion), as a sequelae of spine trauma, as a consequence of a disc herniation with leakage of enzymes onto nerve roots creating scar tissue, or potentially from injections into the spine (although this has not been demonstrated). Such scar tissue is not uniformly painful, but its presence is seen in many patients who have continued or new pain after spine surgery. Dense scar tissue is visible on MRI whereas thin scar tissue strands are not. Since there is no way to directly correlate the pain with the scar tissue through testing, the diagnosis is a presumptive one after ruling out other causes of spinal origin pain. MRI demonstrates scar tissue as a compression of the spinal sac (dura) or nerve tissue. The MRI images can lead to confusion between scar tissue and a new disc herniation, and often gadolinium contrast is injected IV to permit differentiation between scar tissue and new or recurrent disc herniation. Also new fat suppression modes MRI settings coupled with IV gadolinium make the presence of scar tissue quite clear. Epidurography is the injection of the epidural space under x-ray with contrast material which shows scar tissue as a "filling defect". The area where contrast does not go (but should) is presumptively scar tissue or some other obstruction. Often during epidurography, the nerve roots can be evaluated as to whether contrast flows freely down the nerve root or whether there is an obstruction. Finally, epiduroscopy can be used to evaluate scar tissue. Epiduroscopy uses an endoscope placed in the caudal canal in the sacrum (tailbone) and the endoscope is advanced in the spine while assessment of scar tissue is undertaken. Some scar tissue may be easily broken up by the endoscope, while dense scar tissue cannot. In the past, surgeons would operate on scar tissue in the spine over and over again attempting to remove it, but the scar tissue grows back. Because of increasing risks of damage to the spine with more surgeries and because of the short term relief provided by such surgeries, most surgeons do not perform scar tissue excision surgeries any longer.
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